HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 2-nitro-5-(2-oxoethyl)benzoate → Methyl 2-nitro-5-(2-{4-[2-(4-nitrophenyl)ethyl]-3-oxopiperazin-1-yl}ethyl)benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 2-nitro-5-(2-oxoethyl)benzoate | HCID 89524855 | — |
| Reactant | 1-[2-(4-Nitrophenyl)ethyl]piperazin-2-one | HCID 89524891 | — |
| Product | Methyl 2-nitro-5-(2-{4-[2-(4-nitrophenyl)ethyl]-3-oxopiperazin-1-yl}ethyl)benzoate | HCID 89533512 | — |
Reaction Steps
The title compound was prepared from 1-[2-(4-Nitrophenyl)ethyl]piperazin-2-one and Methyl 2-nitro-5-(2-oxoethyl)benzoate following essentially the same procedure as Example 6. The product was purified by mass-directed reverse phase HPLC (AcCN-Water with 0.1% TFA). LC-MS (IE, m/z): 457 [M+1]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999990B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-acf3bc05a9704b6c816690b1c90a4687 |
| Source note | uspto-grants-2015_04 |