Acetic Acid → 4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-imidic Acid Ethyl Ester

HRID 146615Notes

Reaction equation

HRID 146615 reaction equation
[C:5](#[N:6])[N:7]1[CH2:8][CH2:9][N:10]([c:13]2[n:14][c:15]3[cH:16][c:17]([O:26][CH3:27])[c:18]([O:24][CH3:25])[cH:19][c:20]3[c:21]([NH2:23])[n:22]2)[CH2:11][CH2:12]1.[CH3:1][CH2:2][OH:3].[CH3:28][C:29](=[O:30])[OH:31].[Na:4]>>[CH3:1][CH2:2][O:3][C:5](=[NH:6])[N:7]1[CH2:8][CH2:9][N:10]([c:13]2[n:14][c:15]3[cH:16][c:17]([O:26][CH3:27])[c:18]([O:24][CH3:25])[cH:19][c:20]3[c:21]([NH2:23])[n:22]2)[CH2:11][CH2:12]1

Participants

5

Reactant 4

HCID 176Acetic AcidHCID 702EthanolHCID 5360545SodiumHCID 213933662-(4-Cyanopiperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline

Product 1

HCID 541908694-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazine-1-imidic Acid Ethyl Ester

Sources & evidence

ORD record
ord-46f9b639da9e4383907d5235be44400a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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