Potassium Carbonate → HCID 66825665, compound

HRID 1466396Notes

Reaction equation

Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=1[CH:11]=[O:12].[F:13][CH:14]([F:22])[C:15]1[CH:16]=[C:17]([OH:21])[CH:18]=[CH:19][CH:20]=1.C(=O)([O-])[O-:24].[K+].[K+]>>[F:9][CH:8]([F:10])[C:4]1[C:3]([C:11]([OH:12])=[O:24])=[C:2]([O:21][C:17]2[CH:18]=[CH:19][CH:20]=[C:15]([CH:14]([F:22])[F:13])[CH:16]=2)[N:6]([CH3:7])[N:5]=1

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 27696123-DIFLUOROMETHYLPHENOL

HCID 197546925-Chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde

Product 1

HCID 66825665HCID 66825665, compound

Procedure

The title compound was prepared using 5-chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde and 3-difluoromethylphenol in the manner similar to the method in Production Example 1 above except potassium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record: ord-3f6de6a550284cb2871b89b60d543e91
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000024B2

Reaction notes

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