Potassium Carbonate → HCID 66825864, compound

HRID 1466397Notes

Reaction equation

Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[C:3]=1[CH:12]=[O:13].[F:14][CH:15]([F:23])[C:16]1[CH:17]=[C:18]([OH:22])[CH:19]=[CH:20][CH:21]=1.C(=O)([O-])[O-:25].[K+].[K+]>>[F:14][CH:15]([F:23])[C:16]1[CH:17]=[C:18]([CH:19]=[CH:20][CH:21]=1)[O:22][C:2]1[N:6]([CH3:7])[N:5]=[C:4]([C:8]([F:11])([F:10])[F:9])[C:3]=1[C:12]([OH:13])=[O:25]

Participants

Reactant 3

HCID 11430Potassium Carbonate

HCID 14784595-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde

HCID 27696123-DIFLUOROMETHYLPHENOL

Product 1

HCID 66825864HCID 66825864, compound

Procedure

The title compound was prepared using 5-chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazole-4-carbaldehyde and 3-difluoromethylphenol in the manner similar to the method in Production Example 1 above except potassium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record: ord-e870faf00f9a47258897694230433d5f
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000024B2

Reaction notes

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