2-Thiophenesulfonyl chloride → HCID 25213949, compound

HRID 1466494Notes

Reaction equation

HRID 1466494 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[N+:16]([O-])=O.[S:19]1[CH:23]=[CH:22][CH:21]=[C:20]1[S:24](Cl)(=[O:26])=[O:25]>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]1[NH:8][C:9]2[C:14]([CH:15]=1)=[CH:13][CH:12]=[CH:11][C:10]=2[NH:16][S:24]([C:20]1[S:19][CH:23]=[CH:22][CH:21]=1)(=[O:26])=[O:25]

Participants

3

Reactant 2

HCID 855182-Thiophenesulfonyl chlorideHCID 57901748HCID 57901748, compound

Product 1

HCID 25213949HCID 25213949, compound

Procedure

2-Pyridin-2-yl-7-nitro-1H-indole prepared in Preparation 9 and 2-thiophenesulfonylchloride were reacted according to the same procedures as Step A of Example 1 and Example 22 sequentially to give the title compound.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-e8dd58b2e16144f0b2008a752168dc8a
Source dataset
uspto-grants-2015_04
Patent number
US09000028B2

Reaction notes

Loading…