2-Thiophenesulfonyl chloride → HCID 25213950, compound

HRID 1466495Notes

Reaction equation

HRID 1466495 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]([CH3:17])[CH:5]=[C:6]2[C:10]=1[NH:9][C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)=[CH:7]2.[S:18]1[CH:22]=[CH:21][CH:20]=[C:19]1[S:23](Cl)(=[O:25])=[O:24]>>[CH3:17][C:4]1[CH:5]=[C:6]2[C:10](=[C:2]([NH:1][S:23]([C:19]3[S:18][CH:22]=[CH:21][CH:20]=3)(=[O:25])=[O:24])[CH:3]=1)[NH:9][C:8]([C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][N:12]=1)=[CH:7]2

Participants

3

Reactant 2

HCID 855182-Thiophenesulfonyl chlorideHCID 68474590HCID 68474590, compound

Product 1

HCID 25213950HCID 25213950, compound

Procedure

7-Amino-5-methyl-2-(pyridin-2-yl)-1H-indole prepared in Step A of Example 1 and 2-thiophenesulfonylchloride were reacted according to the same procedure as Example 22 to give the title compound.

Sources & evidence

ORD record
ord-b2f8c842c1f64857b9d35010836573ab
Source dataset
uspto-grants-2015_04
Patent number
US09000028B2

Reaction notes

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