Methyl bromoacetate → HCID 68472345, compound

HRID 1466524Notes

Reaction equation

[N+:1]([C:4]1[CH:5]=[C:6]([O:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:7]=[C:8]2[C:12]=1[NH:11][C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:9]2)([O-])=O.Br[CH2:27][C:28]([O:30][CH3:31])=[O:29]>>[CH3:31][O:30][C:28](=[O:29])[CH2:27][NH:1][C:4]1[CH:5]=[C:6]([O:19][C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:7]=[C:8]2[C:12]=1[NH:11][C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:9]2

Participants

Reactant 2

HCID 60984Methyl bromoacetate

HCID 68472960HCID 68472960, compound

Product 1

HCID 68472345HCID 68472345, compound

Procedure

7-Nitro-5-phenoxy-2-phenyl-1H-indole prepared in Preparation 27 and methyl bromoacetate were reacted according to the same procedures as Step A of Example 1 and Example 22 sequentially to give the title compound.

Workup

customwere reacted

Sources & evidence

ORD record: ord-c1988eae52b94e83933e597fd060100d
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000028B2

Reaction notes

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