HRID1466528

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID66974362

未命名化合物

结构：O=C(O)c1cc([N+](=O)[O-])c2[nH]c(-c3ccccc3)cc2c1

HCID68476528

未命名化合物

PRODUCTS

生成物

结构：COC(=O)C[C@H](CSCc1ccc(OC)cc1)NC(=O)c1cc([N+](=O)[O-])c2[nH]c(-c3ccccc3)cc2c1

HCID68477813

未命名化合物

PROCEDURE

实验过程

2-Phenyl-7-nitro-1H-indole-5-carboxylic acid prepared in Preparation 28 and (R)-3-amino-4-(4-methoxy-benzylsulfanyl)-butyric acid methyl ester hydrochloride prepared in Preparation 47 were reacted according to the same procedure as Example 92 to give the title compound.

WORKUP

后处理

customprepared in Preparation 47
customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6ee86bb584164bbb94b5e818f6690ae2
来源数据集: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09000028B2
来源说明: uspto-grants-2015_04

反应 SMILES

[C:1]1([C:7]2[NH:8][C:9]3[C:14]([CH:15]=2)=[CH:13][C:12]([C:16](O)=[O:17])=[CH:11][C:10]=3[N+:19]([O-:21])=[O:20])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[CH3:23][O:24][C:25](=[O:40])[CH2:26][C@@H:27]([NH2:39])[CH2:28][S:29][CH2:30][C:31]1[CH:36]=[CH:35][C:34]([O:37][CH3:38])=[CH:33][CH:32]=1>>[CH3:23][O:24][C:25](=[O:40])[CH2:26][C@@H:27]([NH:39][C:16]([C:12]1[CH:13]=[C:14]2[C:9](=[C:10]([N+:19]([O-:21])=[O:20])[CH:11]=1)[NH:8][C:7]([C:1]1[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1)=[CH:15]2)=[O:17])[CH2:28][S:29][CH2:30][C:31]1[CH:32]=[CH:33][C:34]([O:37][CH3:38])=[CH:35][CH:36]=1