HuagongsheHuagongshe Chemistry Print Report · For research reference only
(R)-3-amino-4-(4-methoxy-benzylsulfanyl)-butyric acid methyl ester hydrochloride → (R)-4-(4-methoxy-benzylsulfanyl)-3-[(7-nitro-2-phenyl-1H-indole-5-carbonyl)-amino]-butyric acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (R)-3-amino-4-(4-methoxy-benzylsulfanyl)-butyric acid methyl ester hydrochloride | HCID 66974362 | — |
| Reactant | 7-Nitro-2-phenyl-1h-indole-5-carboxylic acid | HCID 68476528 | — |
| Product | (R)-4-(4-methoxy-benzylsulfanyl)-3-[(7-nitro-2-phenyl-1H-indole-5-carbonyl)-amino]-butyric acid methyl ester | HCID 68477813 | — |
Reaction Steps
2-Phenyl-7-nitro-1H-indole-5-carboxylic acid prepared in Preparation 28 and (R)-3-amino-4-(4-methoxy-benzylsulfanyl)-butyric acid methyl ester hydrochloride prepared in Preparation 47 were reacted according to the same procedure as Example 92 to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000028B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-6ee86bb584164bbb94b5e818f6690ae2 |
| Source note | uspto-grants-2015_04 |