Benzyl Bromide → [3-(1-Benzyl-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

HRID 1466769Notes

Reaction equation

HRID 1466769 reaction equation
[CH3:1][C:2]1[NH:3][C:4]2[C:9]([C:10]=1[S:11][C:12]1[CH:13]=[C:14]([CH2:18][C:19]([OH:21])=[O:20])[CH:15]=[CH:16][CH:17]=1)=[CH:8][CH:7]=[CH:6][CH:5]=2.[CH2:22](Br)[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[CH2:22]([N:3]1[C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[C:10]([S:11][C:12]2[CH:13]=[C:14]([CH2:18][C:19]([OH:21])=[O:20])[CH:15]=[CH:16][CH:17]=2)=[C:2]1[CH3:1])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

Participants

3

Reactant 2

HCID 7498Benzyl BromideHCID 56840408[3-(2-Methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Product 1

HCID 56840632[3-(1-Benzyl-2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid

Procedure

Prepared according to the procedure described in Example 4, Step 1, using the following starting materials: [3-(2-methyl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid and benzyl bromide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9c0bc43eb1ab437ea688525af8e9a0a2
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

Loading…