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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466773Generated: October 25, 2026

Lithium Hydroxide → 3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid

https://huagongshe.com/reaction/1466773

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl esterHCID 66765236—
SolventMeOH tetrahydrofuranHCID 21899815—
Product3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acidHCID 56840633—

Reaction Steps

3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid methyl ester (0.040 g, 0.086 mmol) was dissolved in THF:MeOH (1:1) then LiOH (1M aq.) was added and the reaction stirred at room temperature overnight. Acid-base extraction afforded the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-16af161da1cf49d7bca79d8b1daf2841
Source noteuspto-grants-2015_04