Iodoethane → 2-[3-(6-Chloro-2-methyl-1-pyridin-3-yl-1H-indol-3-ylsulfanyl)-phenyl]butyric acid ethyl ester

HRID 1466838Notes

Reaction equation

HRID 1466838 reaction equation
[CH2:1]([O:3][C:4](=[O:30])[CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]([C:23]3[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=3)[C:14]=2[CH3:29])[CH:7]=1)[CH3:2].I[CH2:32][CH3:33]>>[CH2:1]([O:3][C:4](=[O:30])[CH:5]([C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([S:12][C:13]2[C:21]3[C:16](=[CH:17][C:18]([Cl:22])=[CH:19][CH:20]=3)[N:15]([C:23]3[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=3)[C:14]=2[CH3:29])[CH:7]=1)[CH2:32][CH3:33])[CH3:2]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 66764872[3-(6-Chloro-2-methyl-1-pyridin-3-yl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid ethyl ester

Product 1

HCID 667653442-[3-(6-Chloro-2-methyl-1-pyridin-3-yl-1H-indol-3-ylsulfanyl)-phenyl]butyric acid ethyl ester

Procedure

Prepared according to the procedure described in Example 108, step 1, using the following starting materials: [3-(6-Chloro-2-methyl-1-pyridin-3-yl-1H-indol-3-ylsulfanyl)-phenyl]-acetic acid ethyl ester and iodoethane.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-fe77513eea214089ae0678681a986bd1
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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