N,N-Dimethylethylenediamine → 3-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-N-(2-dimethylamino-ethyl)-benzamide

HRID 1466888Notes

Reaction equation

HRID 1466888 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([Br:17])[CH:15]=2)[C:10]([S:18][C:19]2[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=2)[C:22](O)=[O:23])=[C:9]1[CH3:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:29][N:30]([CH3:34])[CH2:31][CH2:32][NH2:33]>>[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([Br:17])[CH:15]=2)[C:10]([S:18][C:19]2[CH:20]=[C:21]([CH:25]=[CH:26][CH:27]=2)[C:22]([NH:33][CH2:32][CH2:31][N:30]([CH3:34])[CH3:29])=[O:23])=[C:9]1[CH3:28])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 568406333-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid

Product 1

HCID 680963113-(1-Benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-N-(2-dimethylamino-ethyl)-benzamide

Procedure

Prepared according to the procedure described in Example 89, Step 1 using the following starting materials: 3-(1-benzyl-6-bromo-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid and N,N-dimethylethylenediamine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-8738f6dc60cb4dad9807efa9fb5010a2
Source dataset
uspto-grants-2015_04
Patent number
US09000025B2

Reaction notes

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