HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466911Generated: November 2, 2026
Ethanol → Ethyl 6-chloroindole-2-carboxylate
https://huagongshe.com/reaction/1466911
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 6-Chloro-1H-indole-2-carboxylic acid | HCID 85584 | — |
| Product | Ethyl 6-chloroindole-2-carboxylate | HCID 7015027 | — |
Reaction Steps
6-Chloro-1H-indole-2-carboxylic acid (2.59 g, 13.4 mmol) was dissolved in EtOH (75 mL) and conc. H2SO4 (1 mL) was added. The reaction was heated to 120° C. overnight then submitted to aqueous workup to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09000025B2 |
|---|
| Source dataset | uspto-grants-2015_04 |
|---|
| ORD ID | ord-db477e0effa749ecac46d986b249d986 |
|---|
| Source note | uspto-grants-2015_04 |
|---|
