Lithium Hydroxide → HCID 66765609, compound

Participants

Reaction Conditions

Reaction Steps

1-Benzyl-3-(3-bromo-phenylsulfanyl)-6-chloro-1H-indole-2-carboxylic acid ethyl ester (0.520 g, 1.04 mmol) was dissolved in MeOH:THE (1:1, 10 mL) and LiOH (5 mL, 1.0M aq., 5 mmol) was added. The reaction was heated to 50° C. for 1 hour then removed from heat and submitted to aqueous workup to give the title compound which was carried to the next step without further purification.

Provenance & Evidence