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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466938Generated: October 27, 2026

4-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazole → 3-{6-Chloro-7-fluoro-1-[1-(4-methoxy-benzyl)-1H-pyrazol-4-yl]-2-methyl-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester

https://huagongshe.com/reaction/1466938

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazoleHCID 57421936—
Reactant3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl esterHCID 66765504—
Product3-{6-Chloro-7-fluoro-1-[1-(4-methoxy-benzyl)-1H-pyrazol-4-yl]-2-methyl-1H-indol-3-ylsulfanyl}-benzoic acid ethyl esterHCID 66765785—

Reaction Steps

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: 3-(6-chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-benzoic acid ethyl ester and 4-iodo-1-(4-methoxy-benzyl)-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-54237fe10b364c3d911fcba4c224206b
Source noteuspto-grants-2015_04