HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-{6-Chloro-7-fluoro-1-[1-(4-methoxy-benzyl)-1H-pyrazol-4-yl]-2-methyl-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester → 3-[6-Chloro-7-fluoro-2-methyl-1-(1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-{6-Chloro-7-fluoro-1-[1-(4-methoxy-benzyl)-1H-pyrazol-4-yl]-2-methyl-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester | HCID 66765785 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | 3-[6-Chloro-7-fluoro-2-methyl-1-(1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-benzoic acid ethyl ester | HCID 66764883 | — |
Reaction Steps
3-{6-Chloro-7-fluoro-1-[1-(4-methoxy-benzyl)-1H-pyrazol-4-yl]-2-methyl-1H-indol-3-ylsulfanyl}-benzoic acid ethyl ester (0.10 g, 0.18 mmol) was stirred in neat TFA (4 mL) for 18 hrs.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000025B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-bbd4900e50fe43bcae03225c63550623 |
| Source note | uspto-grants-2015_04 |