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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466960Generated: November 1, 2026

(3-Chloro-2-fluorophenyl)hydrazine hydrochloride → [3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-fluoro-phenyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/1466960

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Chloro-2-fluorophenyl)hydrazine hydrochlorideHCID 25067375—
Reactant[2-Fluoro-3-(2-oxo-propylsulfanyl)-phenyl]-acetic acid ethyl esterHCID 66765216—
Product[3-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-fluoro-phenyl]-acetic acid ethyl esterHCID 66765437—

Reaction Steps

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: [2-Fluoro-3-(2-oxo-propylsulfanyl)-phenyl]-acetic acid ethyl ester and (3-chloro-2-fluoro-phenyl) hydrazine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-e70cdff1dc7c4f9c9b55ec33de5557a2
Source noteuspto-grants-2015_04