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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466963Generated: November 3, 2026

(3-Chloro-2-fluorophenyl)hydrazine hydrochloride → [5-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl ester

https://huagongshe.com/reaction/1466963

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3-Chloro-2-fluorophenyl)hydrazine hydrochlorideHCID 25067375—
Reactant[5-(2-Oxo-propylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl esterHCID 66764895—
Product[5-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl esterHCID 66765688—

Reaction Steps

Prepared according to the procedure described in Example 2, Step 1, using the following starting materials: [5-(2-Oxo-propylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl ester and (3-chloro-2-fluoro-phenyl) hydrazine hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-54a0f35141d64374ae0615874b7a8fe3
Source noteuspto-grants-2015_04