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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1466964Generated: October 31, 2026

4-iodo-1-propyl-1H-pyrazole → {5-[6-Chloro-7-fluoro-2-methyl-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-2-trifluoromethyl-phenyl}-acetic acid ethyl ester

https://huagongshe.com/reaction/1466964

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-iodo-1-propyl-1H-pyrazoleHCID 60136632—
Reactant[5-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl esterHCID 66765688—
Product{5-[6-Chloro-7-fluoro-2-methyl-1-(1-propyl-1H-pyrazol-4-yl)-1H-indol-3-ylsulfanyl]-2-trifluoromethyl-phenyl}-acetic acid ethyl esterHCID 66765684—

Reaction Steps

Prepared according to the procedure described in Example 55, Step 2 using the following starting materials: [5-(6-Chloro-7-fluoro-2-methyl-1H-indol-3-ylsulfanyl)-2-trifluoromethyl-phenyl]-acetic acid ethyl ester and 4-iodo-1-propyl-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000025B2
Source datasetuspto-grants-2015_04
ORD IDord-53baecfa19e24f88916d5fb2cfb780cf
Source noteuspto-grants-2015_04