Diethyl (ethoxymethylene)malonate → HCID 178469592, compound

HRID 1466985Notes

Reaction equation

[CH:1]([O:4][C:5]1[CH:11]=[CH:10][C:8]([NH2:9])=[CH:7][CH:6]=1)([CH3:3])[CH3:2].C([O:14][CH:15]=[C:16]([C:22](OCC)=O)[C:17]([O:19][CH2:20][CH3:21])=[O:18])C>>[OH:14][C:15]1[C:10]2[C:8](=[CH:7][CH:6]=[C:5]([O:4][CH:1]([CH3:3])[CH3:2])[CH:11]=2)[N:9]=[CH:22][C:16]=1[C:17]([O:19][CH2:20][CH3:21])=[O:18]

Participants

Reactant 2

HCID 6871Diethyl (ethoxymethylene)malonate

HCID 821124-Isopropoxyaniline

Product 1

HCID 178469592HCID 178469592, compound

Procedure

Prepared as in Example 1c from 4-isopropoxyaniline and diethyl 2-(ethoxymethylene)malonate as a yellow solid (20%). MS 276 (MH+).

Sources & evidence

ORD record: ord-746426c9a97e43c181ca143a076a2177
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09000054B2

Reaction notes

Loading…