HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → (S)-3-Amino-1-benzylpiperidine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | (S)-tert-Butyl (1-benzylpiperidin-3-yl)carbamate | HCID 10541535 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | (S)-3-Amino-1-benzylpiperidine | HCID 854131 | — |
Reaction Steps
4N HCl in dioxane (1 mL) was added to (S)-tert-butyl 1-benzylpiperidin-3-ylcarbamate (0.5 mmol). The reaction was stirred at room temperature for 30 minutes. The solvent was removed by vacuo. The crude product was progressed to the next step without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08999957B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-87ae1ec91eef4e5992f715c055b4aff8 |
| Source note | uspto-grants-2015_04 |