HCID 89499903, compound → HCID 89499963, compound

HRID 1467811Notes

Reaction equation

HRID 1467811 reaction equation
[N:1]1([CH:6]2[CH2:11][CH2:10][N:9]([C:12]3[CH:21]=[CH:20][CH:19]=[C:18]4[C:13]=3[CH:14]=[CH:15][N:16]=[CH:17]4)[CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1>O=[Pt]=O.O=[Mn]=O>[N:1]1([CH:6]2[CH2:11][CH2:10][N:9]([C:12]3[CH:21]=[CH:20][CH:19]=[C:18]4[C:13]=3[CH2:14][CH2:15][N:16]=[CH:17]4)[CH2:8][CH2:7]2)[CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

4

Reactant 1

HCID 89499903HCID 89499903, compound

Product 1

HCID 89499963HCID 89499963, compoundYield 62.8%

Reagents, catalysts & solvents 2

HCID 14801Manganese dioxideCatalystHCID 345198Adams' catalystCatalyst

Procedure

80A was hydrogenated in the presence of PtO2 and then oxidized with MnO2 to afford 0.85 g (62.8%) of 80B as a yellow oil. MS (ESI) m/z: 284.2 (M+H)+.

Sources & evidence

ORD record
ord-6396c8bbc72a4012b161ccda9f63728f
Source dataset
uspto-grants-2015_04
Patent number
US09000172B2

Reaction notes

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