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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467885Generated: November 2, 2026

4,4-Bis(4-fluorophenyl)butyric acid → HCID 68983959, compound

https://huagongshe.com/reaction/1467885

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4,4-Bis(4-fluorophenyl)butyric acidHCID 88637—
ReactantN-Cyclopropyl-N-piperidin-4-yl-3-(trifluoromethyl)benzenesulfonamideHCID 2773944—
ProductHCID 68983959HCID 68983959—

Reaction Steps

N-Cyclopropyl-N-{1-[4,4-bis(4-fluorophenyl)butanoyl]piperidin-4-yl}-3-trifluoromethylbenzenesulfonamide was prepared from N-cyclopropyl-N-(piperidin-4-yl)-3-trifluoromethylbenzenesulfonamide and 4,4-bis(4-fluorophenyl)butanoic acid. LC: 100%. MS: m/z=607 (M+H+). 1H NMR (CDCl3): δ 8.12 (1H, s), 8.04 (1H, d), 7.86 (1H, d), 7.69 (1H, t), 7.16 (4H, dd), 6.98 (4H, dd), 4.71 (1H, d), 3.98 (1H, d), 3.80 (1H, t), 3.68 (1H, d), 2.91 (1H, t), 2.50 (1H, t), 2.33 (2H, m), 2.21 (2H, m), 1.93 (1H, m), 1.75 (4H, m), 0.91 (4H, m);

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000174B2
Source datasetuspto-grants-2015_04
ORD IDord-bde6926dbf964e18a1a833f5396e1fae
Source noteuspto-grants-2015_04