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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467980Generated: October 26, 2026

N-(1H-indol-5-yl)pivalamide → tert-Butyl 4-((6-(5-pivalamido-1H-indol-1-yl)pyridin-3-yl)oxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1467980

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-(1H-indol-5-yl)pivalamideHCID 11171956—
ReactantTert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylateHCID 86696180—
Producttert-Butyl 4-((6-(5-pivalamido-1H-indol-1-yl)pyridin-3-yl)oxy)piperidine-1-carboxylateHCID 86696182—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-27, using tert-butyl 4-((6-chloropyridin-3-yl)oxy)piperidine-1-carboxylate and N-(1H-indol-5-yl)pivalamide; MS: 437.6 (M−56).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-6112ea0a944f42ca9fb946fdf229e172
Source noteuspto-grants-2015_04