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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467982Generated: October 25, 2026

5-(Methanesulfonyl)-2,3-dihydro-1H-indole → tert-Butyl 4-((6-(5-(methylsulfonyl)indolin-1-yl)pyridin-3-yl)amino)-piperidine-1-carboxylate

https://huagongshe.com/reaction/1467982

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(Methanesulfonyl)-2,3-dihydro-1H-indoleHCID 2736136—
ReactantTert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylateHCID 86602140—
Producttert-Butyl 4-((6-(5-(methylsulfonyl)indolin-1-yl)pyridin-3-yl)amino)-piperidine-1-carboxylateHCID 67606850—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl 4-((6-bromopyridin-3-yl)amino)piperidine-1-carboxylate and 5-(methyl-sulfonyl)indoline; MS: 473.3 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-8cca5f9dcb8941b8ac71b0572aaf9f85
Source noteuspto-grants-2015_04