Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467985Generated: October 26, 2026

5-N-Boc-amino-1H-indole → tert-Butyl 4-((4-(5-amino-1H-indol-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylate

https://huagongshe.com/reaction/1467985

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-N-Boc-amino-1H-indoleHCID 11458923—
Reactanttert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylateHCID 86696185—
Producttert-Butyl 4-((4-(5-amino-1H-indol-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylateHCID 67616897—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-27 using tert-butyl 4((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate and tert-butyl 1H-indol-5-ylcarbamate; MS: 415.1 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-f328571a1a484a539f8422c25a2aa829
Source noteuspto-grants-2015_04