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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1467991Generated: October 26, 2026

Tert-butyl 4-hydroxypiperidine-1-carboxylate → tert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate

https://huagongshe.com/reaction/1467991

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl 4-hydroxypiperidine-1-carboxylateHCID 643502—
Reactant2,4-Dibromo-1,3-thiazoleHCID 2763297—
Producttert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylateHCID 86696185—

Reaction Steps

The title compound was prepared by following the similar procedure as described in Intermediate-42 using tert-butyl 4-hydroxypiperidine-1-carboxylate and 2,4-dibromothiazole (0.1 g, 25%); MS: 363.2 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000175B2
Source datasetuspto-grants-2015_04
ORD IDord-fea8bfd9d6ce458091ba79bbfef08223
Source noteuspto-grants-2015_04