HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Methylsulfonyl)-1H-indole → tert-Butyl-4-((4-(5-(methylsulfonyl)-1H-indol-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Methylsulfonyl)-1H-indole | HCID 14973230 | — |
| Reactant | tert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate | HCID 86696185 | — |
| Product | tert-Butyl-4-((4-(5-(methylsulfonyl)-1H-indol-1-yl)thiazol-2-yl)oxy)-piperidine-1-carboxylate | HCID 67616621 | — |
Reaction Steps
The title compound was prepared by following the similar procedure as described in Example-1 by using 5-(methylsulfonyl)-1H-indole (intermediate 21) and tert-butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate (intermediate 46) (0.007 g, 5%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000175B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-b9c915ec017945bfa065e6ed77286cdf |
| Source note | uspto-grants-2015_04 |