HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(1H-1,2,4-triazol-1-yl)-1H-indole → tert-Butyl-4-((4-(5-(1H-1,2,4-triazol-1-yl)-1H-indol-1-yl)thiazol-2-yl) oxy)piperidine-1-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(1H-1,2,4-triazol-1-yl)-1H-indole | HCID 67616878 | — |
| Reactant | tert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate | HCID 86696185 | — |
| Product | tert-Butyl-4-((4-(5-(1H-1,2,4-triazol-1-yl)-1H-indol-1-yl)thiazol-2-yl) oxy)piperidine-1-carboxylate | HCID 67808899 | — |
Reaction Steps
The title compound was prepared by following the similar procedure as described in Example-1 using tert-Butyl 4-((4-bromothiazol-2-yl)oxy)piperidine-1-carboxylate (intermediate 46) and 5-(1H-1,2,4-triazol-1-yl)-1H-indole (intermediate 58).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000175B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-bc08b4450d8f41b99323a2b9316254d8 |
| Source note | uspto-grants-2015_04 |