Sodium Carbonate → HCID 86710051, compound

Participants

Reaction Steps

2-Isopropyl-6-methylimidazo[1,2-a]pyridine-7-carbonitrile (500 mg, 2.51 mmol) obtained in step 2 was dissolved in DMF (3.0 mL), and the solution was stirred at room temperature for 6 hours under light shielding after adding N-iodosuccinimide (621 mg, 2.76 mmol). A sodium carbonate aqueous solution was added to the reaction mixture. The precipitated crystals were collected by filteration, and dried under reduced pressure to give 3-iodo-2-isopropyl-6-methylimidazo[1,2-a]pyridine-7-carbonitrile (752 mg, yield 92%).

Provenance & Evidence