HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86710068, compound → HCID 86710067, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86710068 | HCID 86710068 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 86710067 | HCID 86710067 | 95.3% |
Reaction Steps
3-(4,4-Difluorocyclohexyl)-1-(1-trifluoromethylcyclopropyl)propan-2-en-1-one (0.746 g, 2.64 mmol) obtained in step 2 was dissolved in ethanol (10 mL), and allowed to react at 25° C. in the full H2 mode of an H-cube (registered trademark) using 10% Pd/C CatCart (30 mm) (ThalesNano Technologies) to give 3-(4,4-difluorocyclohexyl)-1-(1-trifluoromethylcyclopropyl)propan-1-one (0.715 g, yield 95%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09000186B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-6f82496ea4274fbe9d6b71d7e6b11a36 |
| Source note | uspto-grants-2015_04 |