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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468289Generated: November 2, 2026

Aniline → 2-Amino-3-chloro-4-pyridinecarbonitrile

https://huagongshe.com/reaction/1468289

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAnilineHCID 6115—
ReactantHCID 89953962HCID 89953962—
ReactantHCID 89954197HCID 89954197—
Product2-Amino-3-chloro-4-pyridinecarbonitrileHCID 86710097—

Reaction Steps

Compound 107 (40.9 mg, yield 69%) was obtained in the same manner as in step 4 of Example 21, using 6-chloro-3-(4,4-difluorocyclohexylmethyl)-2-trifluoromethylimidazo[1,2-a]pyridine-7-carboxylic acid obtained in step 3, and aniline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09000186B2
Source datasetuspto-grants-2015_04
ORD IDord-adcdd64cbf7b454cbff2bb774dce4920
Source noteuspto-grants-2015_04