HRID1468319

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID8471

Triethylamine

C6H15N

HCID181649

3H-1,2,3-Triazolo[4,5-b]pyridine, 3-hydroxy-

C5H4N4O

结构：CN(C)C(On1nnc2cccnc21)=[N+](C)C.F[P-](F)(F)(F)(F)F

HCID9886157

Methanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)

C10H15F6N6OP

HCID13338715

Methyl 3-amino-2-methoxybenzoate

C9H11NO3

结构：CC(C)(C)OC(=O)N[C@@H](CCC(=O)O)C(=O)OC(C)(C)C.Cl

HCID131731743

未命名化合物

PRODUCTS

生成物

结构：COc1c(NC(=O)CC[C@H](N)C(=O)O)cccc1C(=O)O

HCID66615081

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

HATU, 84 mg (0.2 mmol), 30 mg (0.2 mmol) of HOAt, 61 mg (0.2 mmol) of Boc-Glu-OtBu hydrochloride, 0.084 ml (0.6 mmol) of triethylamine and 1 ml of dichloromethane were added to 36 mg (0.2 mmol) of methyl 2-methoxy-3-aminobenzoate. The mixture was stirred at room temperature overnight.