Hydrochloric Acid → 2-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N,N-dimethyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

HRID 146878Notes

Reaction equation

HRID 146878 reaction equation
[CH3:29][NH:30][CH3:31].[ClH:28].[NH2:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12]([C:18](=[O:19])[OH:20])[cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([N:21]2[CH2:22][CH2:23][N:24]([CH3:27])[CH2:25][CH2:26]2)[cH:5][c:6]([N:8]2[CH2:9][c:10]3[cH:11][c:12]([C:18](=[O:19])[N:30]([CH3:29])[CH3:31])[cH:13][cH:14][c:15]3[CH2:16][CH2:17]2)[n:7]1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 674DimethylamineHCID 594022702-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-1,2,3,4-tetrahydroisoquinoline-7-carboxylic acid

Product 1

HCID 467013862-[2-Amino-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]-N,N-dimethyl-1,2,3,4-tetrahydroisoquinoline-7-carboxamide

Sources & evidence

ORD record
ord-9e23e9c309744fd98d5bfee11fa5fed9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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