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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468813Generated: October 30, 2026

5,8-Dibromoimidazo[1,2-a]pyrazine → N-(5-bromoimidazo[1,2-a]pyrazin-8-yl)-5-((tert-butyldimethylsilyloxy)methyl)thiazol-2-amine

https://huagongshe.com/reaction/1468813

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5,8-Dibromoimidazo[1,2-a]pyrazineHCID 53485949—
Reactant5-(((tert-Butyldimethylsilyl)oxy)methyl)thiazol-2-amineHCID 57541328—
ProductN-(5-bromoimidazo[1,2-a]pyrazin-8-yl)-5-((tert-butyldimethylsilyloxy)methyl)thiazol-2-amineHCID 57541342—

Reaction Steps

Prepared from Intermediate 2 and Intermediate 7 using the procedure described in Example 1, Step 1. MS (MH+, m/z) 440.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09006237B2
Source datasetuspto-grants-2015_04
ORD IDord-e776fa2d772041bead1be1f1419ddcfe
Source noteuspto-grants-2015_04