HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86717786, compound → {(1R,2R)-2-[1-(5-isopropylpyrimidin-2-yl)piperidin-4-yl]cyclopropyl}methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86717786 | HCID 86717786 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | {(1R,2R)-2-[1-(5-isopropylpyrimidin-2-yl)piperidin-4-yl]cyclopropyl}methanol | HCID 71128800 | — |
Reaction Steps
The product of step A (170 mg, 0.62 mmol) and 5% Pd/C (20 mg) were dissolved in EtOH (5 mL). The mixture was stirred under 1 atm of H2 for 1 hour. The mixture was filtered and the filtrate concentrated in vacuo, yielding the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006228B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-bbdfca2ecc5a4dc8aa1dfb559566d024 |
| Source note | uspto-grants-2015_04 |