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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1468836Generated: October 26, 2026

Iodide Ion → 2-{4-[(1R,2R)-2-(iodomethyl)cyclopropyl]piperidin-1-yl}-5-isopropylpyrimidine

https://huagongshe.com/reaction/1468836

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodide IonHCID 30165—
Reactant{(1R,2R)-2-[1-(5-isopropylpyrimidin-2-yl)piperidin-4-yl]cyclopropyl}methanolHCID 71128800—
Product2-{4-[(1R,2R)-2-(iodomethyl)cyclopropyl]piperidin-1-yl}-5-isopropylpyrimidineHCID 86717787—

Reaction Steps

The product of step B was converted to the iodide using the conditions outlined for intermediate 8, step A.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09006228B2
Source datasetuspto-grants-2015_04
ORD IDord-dbcab2cb3d30481f8542a537e3d1f19c
Source noteuspto-grants-2015_04