HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 86692256, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(Trifluoromethyl)phenol | HCID 67874 | — |
| Reactant | 1-Chloro-5-nitroisoquinoline | HCID 459774 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86692256 | HCID 86692256 | 100.1% |
Reaction Steps
The title compound was prepared following the procedure described in Intermediate-6, step-1 using 1-chloro-5-nitroisoquinoline (Step-1, Intermediate-1, 500 mg, 2.39 mmol), 4-(trifluoromethyl)phenol (776 mg, 4.79 mmol) and K2CO3 (989 mg, 7.17 mmol) in CH3CN (5 mL) to afford 800 mg of the title product. MS (m/z): 335.09 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006257B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-ee12568beee94b228ec53807096ec3da |
| Source note | uspto-grants-2015_04 |