HuagongsheHuagongshe Chemistry Print Report · For research reference only
Morpholine → HCID 71678382, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | HCID 86692243 | HCID 86692243 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 71678382 | HCID 71678382 | 78.1% |
Reaction Steps
The title compound was prepared following the procedure described in Intermediate-15, step-1 using 4-chloro-2-methyl-8-nitroquinazoline (Intermediate-27, step-2, 280 mg, 1.26 mmol), morpholine (219 mg, 2.52 mmol), and K2CO3 (521 mg, 3.78 mmol) in CH3CN (5 mL) to afford 270 mg of the title product. MS [M+H]+: 275.22.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006257B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-688a1bc29327439d877f343531dfb110 |
| Source note | uspto-grants-2015_04 |