Tert-Butylamine → HCID 86692261, compound

Participants

Reaction Steps

The title compound was prepared following the procedure described in Intermediate-55, step-1 using 4-chloro-2-methyl-8-nitroquinazoline (Intermediate-27, step-2, 300 mg, 1.34 mmol), and tert-butylamine (196 mg, 2.68 mmol) in pyridine (5 mL) to afford 200 mg of the title product. 1H NMR (300 MHz, DMSO d6): δ 8.62-8.59 (d, J=8.1 Hz, 1H), 8.16-8.13 (d, J=7.5 Hz, 1H), 7.61 (s, 1H), 7.51 (t, J=7.8 Hz, 1H), 2.45 (s, 3H), 1.55 (s, 9H); MS (m/z): 261.20 (M+H)+.

Provenance & Evidence