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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1469984Generated: November 1, 2026

Iodoethane → HCID 178462562, compound

https://huagongshe.com/reaction/1469984

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodoethaneHCID 6340—
Reactant1-Adamantanecarboxylic acidHCID 13235—
Reactant2-Amino-4,5-dimethyl-1,3-thiazoleHCID 73238—
ProductHCID 178462562HCID 178462562—

Reaction Steps

4,5-Dimethylthiazol-2-ylamine, iodoethane and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.20-1.29 (m, 3H) 1.68 (q, J=11.96 Hz, 6H) 1.84 (d, J=2.50 Hz, 6H) 1.94-2.03 (m, 3H) 2.16 (s, 3H) 2.21 (s, 3H) 4.14 (q, J=7.18 Hz, 2H); MS (ESI) m/z 319 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09006275B2
Source datasetuspto-grants-2015_04
ORD IDord-7ab5e8525a8d4a77b9f381356743f4f7
Source noteuspto-grants-2015_04