Iodoethane → HCID 178462562, compound

HRID 1469984Notes

Reaction equation

HRID 1469984 reaction equation
[CH3:1][C:2]1[N:3]=[C:4]([NH2:8])[S:5][C:6]=1[CH3:7].I[CH2:10][CH3:11].[C:12]12([C:22](O)=[O:23])[CH2:21][CH:16]3[CH2:17][CH:18]([CH2:20][CH:14]([CH2:15]3)[CH2:13]1)[CH2:19]2>>[CH2:10]([N:3]1[C:2]([CH3:1])=[C:6]([CH3:7])[S:5]/[C:4]/1=[N:8]\[C:22]([C:12]12[CH2:21][CH:16]3[CH2:17][CH:18]([CH2:20][CH:14]([CH2:15]3)[CH2:13]1)[CH2:19]2)=[O:23])[CH3:11]

Participants

4

Reactant 3

HCID 6340IodoethaneHCID 132351-Adamantanecarboxylic acidHCID 732382-Amino-4,5-dimethyl-1,3-thiazole

Product 1

HCID 178462562HCID 178462562, compound

Procedure

4,5-Dimethylthiazol-2-ylamine, iodoethane and 1-adamantane carboxylic acid were processed according to the method of Example 47 to afford the title compound. 1H NMR (CDCl3, 500 MHz) δ ppm 1.20-1.29 (m, 3H) 1.68 (q, J=11.96 Hz, 6H) 1.84 (d, J=2.50 Hz, 6H) 1.94-2.03 (m, 3H) 2.16 (s, 3H) 2.21 (s, 3H) 4.14 (q, J=7.18 Hz, 2H); MS (ESI) m/z 319 (M+H)+.

Sources & evidence

ORD record
ord-7ab5e8525a8d4a77b9f381356743f4f7
Source dataset
uspto-grants-2015_04
Patent number
US09006275B2

Reaction notes

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