2-Bromoethyl methyl ether → 5-Methoxy-3-(2-methoxyethyl)thiazol-2(3h)-imine hydrobromide
Reaction equation
[CH3:1][O:2][C:3]1[S:7][C:6]([NH2:8])=[N:5][CH:4]=1.[CH3:9][O:10][CH2:11][CH2:12][Br:13]>>[BrH:13].[CH3:1][O:2][C:3]1[S:7][C:6](=[NH:8])[N:5]([CH2:12][CH2:11][O:10][CH3:9])[CH:4]=1Participants
3
Procedure
A mixture of Example 185A and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 189 (M+H)+.
Sources & evidence
- ORD record
- ord-0514449dc4b549698f55dd7162df8d5f
- Source dataset
- uspto-grants-2015_04
- Patent number
- US09006275B2
Reaction notes
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