2-Bromoethyl methyl ether → HCID 87181446, compound

HRID 1470039Notes

Reaction equation

HRID 1470039 reaction equation
[NH2:1][C:2]1[S:3][C:4]([C:8]([OH:17])([C:13]([F:16])([F:15])[F:14])[C:9]([F:12])([F:11])[F:10])=[C:5](C)[N:6]=1.[CH3:18][O:19][CH2:20][CH2:21][Br:22]>>[BrH:22].[F:12][C:9]([F:10])([F:11])[C:8]([C:4]1[S:3][C:2](=[NH:1])[N:6]([CH2:21][CH2:20][O:19][CH3:18])[CH:5]=1)([OH:17])[C:13]([F:16])([F:15])[F:14]

Participants

3

Reactant 2

HCID 809722-Bromoethyl methyl etherHCID 113579532-(2-Amino-4-methylthiazol-5-yl)-1,1,1,3,3,3-hexafluoropropan-2-ol

Product 1

HCID 87181446HCID 87181446, compound

Procedure

A mixture of Example 186A and commercially available 2-bromoethyl methyl ether (Aldrich) was processed using the method described in Example 46A to afford the title compound. MS (ESI+) m/z 325 (M+H)+.

Sources & evidence

ORD record
ord-831ec0cb0a204b7c961b711a69aa5b9e
Source dataset
uspto-grants-2015_04
Patent number
US09006275B2

Reaction notes

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