Lithium Hydroxide → HCID 66778978, compound

Participants

Reaction Steps

3-Methyl-5-(7-phenyl-furo[3,2-b]pyridin-2-yl)-benzoic acid methyl ester (61.321 μmol) is dissolved in THF (300.00 μl) and LiOH 1M (122,600 μmol) is added. The reaction solution is stirred 26 h at RT and diluted with H2O (10 ml) and 1M HCl (122.6 μl) is added. The precipitate is filtered and washed with water and dried in vacuo. The product is obtained as colorless solid in quantitative yield; LCMS (ESI+) (method E): Rt 2.25 min, M+H+ 330.1 m/z.

Provenance & Evidence