HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Aminomethyltetrahydropyran → 1-Chloro-5-methyl-N-((tetrahydro-2H-pyran-4-yl)methyl)isoquinolin-4-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Aminomethyltetrahydropyran | HCID 2773210 | — |
| Reactant | HCID 84687221 | HCID 84687221 | — |
| Product | 1-Chloro-5-methyl-N-((tetrahydro-2H-pyran-4-yl)methyl)isoquinolin-4-carboxamide | HCID 86689578 | — |
Reaction Steps
The title compound was prepared by using 1-chloro-5-methylisoquinolin-4-carboxylic acid (Intermediate-10) and (tetrahydro-2H-pyran-4-yl)methanamine by following the similar procedure as described for Intermediate-11a.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09006442B2 |
| Source dataset | uspto-grants-2015_04 |
| ORD ID | ord-962ff391de5c4273b9195c239c92dad9 |
| Source note | uspto-grants-2015_04 |