Trifluoromethanesulfonic anhydride → HCID 88921376, compound

HRID 1470495Notes

Reaction equation

[OH:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)=[O:14])=[CH:4][CH:3]=1.[O:20](S(C(F)(F)F)(=O)=O)[S:21]([C:24]([F:27])([F:26])[F:25])(=O)=[O:22]>>[F:25][C:24]([F:27])([F:26])[S:21]([O:1][C:2]1[C:11]2[C:6](=[C:7]([CH3:12])[CH:8]=[CH:9][CH:10]=2)[C:5]([C:13]([N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)=[O:14])=[CH:4][CH:3]=1)(=[O:22])=[O:20]

Participants

Reactant 2

HCID 67749Trifluoromethanesulfonic anhydride

HCID 68282084HCID 68282084, compound

Product 1

HCID 88921376HCID 88921376, compound

Procedure

This compound was prepared by treating (4-hydroxy-8-methylnaphthalen-1-yl) (pyrrolidin-1-yl)methanone (above step-2 intermediate) with Tf2O by following the similar procedure as described in Step-8 of Intermediate-22.

Workup

customThis compound was prepared

Sources & evidence

ORD record: ord-95223c5506e44826ac50e6e0bea54985
Source dataset: uspto-grants-2015_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09006442B2

Reaction notes

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