Hydrochloric Acid → HCID 85085907, compound

Participants

Reaction Conditions

Reaction Steps

To a slurry of 4-bromo-phenylamine (10 g, 58.13 mmol) in water (200 mL) was added chloral hydrate (11.65 g, 69.76 mmol), sodium sulphate (50 g), hydroxylamine hydrochloride (12.8 g, 186 mmol) and conc. HCl (15 mL). The reaction mixture was then heated to 85° C. and stirred for another 2 h. After completion of the reaction, a solid separated out. The mixture was cooled to room temperature, filtered and washed with water (2-3 times) and dried to obtain the title compound as off white solid (12 g, 84.9%).

Provenance & Evidence