Hydrochloric Acid → Benzoic acid, 4-(phenylsulfonyl)-

HRID 1470634Notes

Reaction equation

HRID 1470634 reaction equation
[C:1]1([S:7]([C:9]2[CH:17]=[CH:16][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=2)=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.Cl[O-:20].[Na+]>>[C:1]1([S:7]([C:9]2[CH:17]=[CH:16][C:12]([C:13]([OH:15])=[O:14])=[CH:11][CH:10]=2)(=[O:20])=[O:8])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 3438114-Benzenesulfinyl-benzoic acidHCID 23665760Sodium Hypochlorite

Product 1

HCID 79322Benzoic acid, 4-(phenylsulfonyl)-Yield 70%

Procedure

4-Benzenesulfinyl-benzoic acid (0.14 g, 0.5 mmol) was suspended in sodium hypochlorite solution (10 mL) and the reaction mixture stirred for 24 h at room temperature. The progress of the reaction was monitored by TLC. The reaction mixture was acidified with an aq. solution of 10% HCl solution. The resulting precipitate was filtered and washed with water. The residue was then redissolved in methanol and concentrated to get the title compound (0.105 g, 70%).

Workup

  1. filtrationThe resulting precipitate was filtered
  2. washwashed with water
  3. dissolutionThe residue was then redissolved in methanol
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-2e5610a6c61c4342a3b8c83ac0011e63
Source dataset
uspto-grants-2015_04
Patent number
US09006454B2

Reaction notes

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